Nathan T. Connell, MD, MPH, FACP is Chief of Medicine at Brigham and Women's Faulkner Hospital, Vice Chair of Medicine for BWFH Clinical Services and Education at Brigham and Women's Hospital, Associate Director of the Boston Hemophilia Center, and an Associate Professor of Medicine at Harvard Medical School.
Dr. Connell earned his Bachelor of Science in Biological Sciences at Cornell University and his Doctor of Medicine from the University of Miami. He subsequently completed his internal medicine residency at Brown University and Rhode Island Hospital, where he also served as chief medical resident. He stayed at Brown to complete his fellowship in hematology and medical oncology while also earning his Master of Public Health degree in Clinical Effectiveness at the Harvard School of Public Health.
His work focuses on the spectrum of von Willebrand factor in health and disease. An excess of von Willebrand factor, due to a deficiency of its cleaving protease ADAMTS13, leads to the life-threatening disorder thrombotic thrombocytopenic purpura. On the other extreme, an inherited or acquired deficiency of VWF leads to bleeding, including von Willebrand disease, the most common inherited bleeding disorder.
In partnership with the American Society of Hematology (ASH), he helped define the field of systems-based hematology, and his research includes the application of decision-analytic models to evaluate the most cost-effective strategies for the diagnosis and treatment of hematologic conditions. He has shown that rapid turnaround of clinical laboratory information significantly reduces unnecessary blood plasma utilization at a health-systems level. He is past chair of the ASH Working Group on Systems-Based Hematology and prior faculty for the ASH Medical Educators Institute.
